Anti-trans Rep. Nancy Mace (R-SC), who regularly uses anti-trans slurs and calls herself a proud transphobe, is getting called totally befuddled and accused of having a sharp mental decline by many on her side of the aisle.Mace was a fairly middle-of-the-road Republican until last year, when she started acting out more and more in public. First, she began her scorched-earth campaign against trans Rep. Sarah McBride (D-DE), which included writing hundreds of posts on social media attacking her in a matter of days. Mace also gave speeches in the House, accusing her ex-fiance of sex crimes (hes suing) and making claims of people threatening and physically attacking her. She recently capped it all off by allegedly throwing a temper tantrum at an airport because security didnt meet her at her car. Related Nancy Mace falsely accused this doctor of child abuse & she lost her job. Shes running for Senate. Her fellow Republicans are calling her out for her erratic behavior. Even some members of her own staff are worried about her mental health.CNNs Jake Tapper reported that a former senior staffer in her office said, It went from kind of funny to devastatingly sad in terms of her not getting help and displaying this behavior on a national stage. Insights for the LGBTQ+ community Subscribe to our briefing for insights into how politics impacts the LGBTQ+ community and more. Subscribe to our Newsletter today Tapper said that an anonymous House Republican said that her colleagues are totally befuddled and that her actions are a big question within the conference.The general feeling is that there is something unwell about her, the House Republican said. Shes really going through a crisis. Its sad. Clearly, there is something going on with her.Maces former consultant, Wesley Donehue, who has traded barbs with Mace in the past, told Tapper: Over the past two to three years,Nancy Mace has been having asharp mental decline. Im nodoctor, but thats what Ibelieve.Shewent from being a very reasonableperson to being someone whocannot control her emotions, he continued.The House Republicantold me that there isnt anyreal infrastructure for theHouse Republican leadership todeal with this type ofsituation, Tapper said. GOP lawmaker: Rep. Nancy Mace's House colleagues "totally befuddled" with her recent behaviorWatch the video here: https://t.co/vawJ6o2lBl pic.twitter.com/PmxbpSDa8W The Lead CNN (@TheLeadCNN) November 6, 2025Subscribe to theLGBTQ Nation newsletterand be the first to know about the latest headlines shaping LGBTQ+ communities worldwide.